- 专利标题: Antibodies directed to PDGFD and uses thereof
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申请号: US10041860申请日: 2002-01-07
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公开(公告)号: US07135174B2公开(公告)日: 2006-11-14
- 发明人: Jose R. F. Corvalan , Xiao-Chi Jia , Xiao Feng , Xiao-dong Yang , Francine Chen , Gadi Gazit , Richard Weber , Binyam Bezabeh
- 申请人: Jose R. F. Corvalan , Xiao-Chi Jia , Xiao Feng , Xiao-dong Yang , Francine Chen , Gadi Gazit , Richard Weber , Binyam Bezabeh
- 申请人地址: US CA Fremont
- 专利权人: Amgen Fremont, Inc.
- 当前专利权人: Amgen Fremont, Inc.
- 当前专利权人地址: US CA Fremont
- 代理机构: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/22
摘要:
The present invention is related to antibodies directed to the antigen PDGFD and uses of such antibodies. In particular, in accordance with the present invention, there are provided fully human monoclonal antibodies directed to the antigen PDGFD. Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
公开/授权文献
- US20030157109A1 Antibodies directed to PDGFD and uses thereof 公开/授权日:2003-08-21