发明授权
- 专利标题: Rapidly disintegrating tablet comprising an acid-labile active ingredient
- 专利标题(中): 包含酸不稳定活性成分的快速崩解片剂
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申请号: US10433397申请日: 2001-12-06
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公开(公告)号: US07147869B2公开(公告)日: 2006-12-12
- 发明人: Rango Dietrich , Hartmut Ney , Rudolf Linder
- 申请人: Rango Dietrich , Hartmut Ney , Rudolf Linder
- 申请人地址: DE Constance
- 专利权人: Altana Pharma AG
- 当前专利权人: Altana Pharma AG
- 当前专利权人地址: DE Constance
- 代理机构: Nath & Associates PLLC
- 代理商 Joshua B. Goldberg; Sheldon M. McGee
- 优先权: EP00126807 20001207
- 国际申请: PCT/EP01/14340 WO 20011206
- 国际公布: WO02/45694 WO 20020613
- 主分类号: A61K9/46
- IPC分类号: A61K9/46
摘要:
A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.
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