- 专利标题: Receptor-mediated gene delivery using bacteriophage vectors
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申请号: US10171407申请日: 2002-06-12
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公开(公告)号: US07148202B2公开(公告)日: 2006-12-12
- 发明人: David Larocca , Andrew Baird , Wendy Johnson
- 申请人: David Larocca , Andrew Baird , Wendy Johnson
- 申请人地址: US CA San Diego
- 专利权人: Selective Genetics, Inc.
- 当前专利权人: Selective Genetics, Inc.
- 当前专利权人地址: US CA San Diego
- 代理机构: Seed IP Law Group PLLC
- 主分类号: A61K31/711
- IPC分类号: A61K31/711 ; C12N15/00 ; C12N15/11
摘要:
Filamentous phage particles displaying a ligand on their surface are used to deliver a therapeutic gene to a cell. The ligand is a fusion protein with a phage capsid protein, covalently conjugated to phage particles, or complexed with modified phage particles.
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