- 专利标题: Diphenylmethyl compounds useful as muscarinic receptor antagonists
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申请号: US11337451申请日: 2006-01-23
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公开(公告)号: US07151115B2公开(公告)日: 2006-12-19
- 发明人: Mathai Mammen , Yu-Hua Ji , Sarah Dunham , Li Li
- 申请人: Mathai Mammen , Yu-Hua Ji , Sarah Dunham , Li Li
- 申请人地址: US CA South San Francisco
- 专利权人: Theravance, Inc.
- 当前专利权人: Theravance, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理商 Jeffrey A. Hagenah; Shelley Eberle
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61K31/445
摘要:
This invention provides compounds of formula I: wherein a, b, c, e, m, R1, R2, R3, R4a, R4b, R5, R6, R7 and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
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