- Patent Title: Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
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Application No.: US10733877Application Date: 2003-12-12
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Publication No.: US07153847B2Publication Date: 2006-12-26
- Inventor: Jing Wu , Jay S. Tung , Jeffrey S. Nissen , R. Jeffrey Neitz , James A. Audia , Thomas E. Mabry
- Applicant: Jing Wu , Jay S. Tung , Jeffrey S. Nissen , R. Jeffrey Neitz , James A. Audia , Thomas E. Mabry
- Applicant Address: US CA South San Francisco US IN Indianapolis
- Assignee: Athena Neurosciences, Inc.,Eli Lilly and Company
- Current Assignee: Athena Neurosciences, Inc.,Eli Lilly and Company
- Current Assignee Address: US CA South San Francisco US IN Indianapolis
- Agent Robert D. Titus
- Main IPC: C07D487/00
- IPC: C07D487/00 ; C07D491/00 ; A61K31/55
Abstract:
Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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