- 专利标题： Polymorphs of an epothilone analog
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申请号： US11271456申请日： 2005-11-10
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公开(公告)号： US07153879B2公开(公告)日： 2006-12-26
- 发明人: John D. DiMarco , Jack Z. Gougoutas , Imre M. Vitez , Martha Davidovich , Michael A. Galella , Timothy M. Malloy , Zhenrong Guo , Denis Favreau
- 申请人： John D. DiMarco , Jack Z. Gougoutas , Imre M. Vitez , Martha Davidovich , Michael A. Galella , Timothy M. Malloy , Zhenrong Guo , Denis Favreau
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Gary D. Greenblatt
- 主分类号： C07D493/04
- IPC分类号： C07D493/04 ; A61K31/42 ; A61P35/00
摘要：
There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
公开/授权文献
- US20060063815A1 Polymorphs of an epothilone analog 公开/授权日：2006-03-23
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