发明授权
- 专利标题: CDNA encoding the human α2 δ4 calcium channel subunit
- 专利标题(中): CDNA编码人α2δ4钙通道亚基
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申请号: US10119624申请日: 2002-04-10
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公开(公告)号: US07157248B2公开(公告)日: 2007-01-02
- 发明人: Ning Qin , Ellen Codd
- 申请人: Ning Qin , Ellen Codd
- 申请人地址: US NJ Raritan
- 专利权人: Ortho-McNeil Pharmaceutical, Inc.
- 当前专利权人: Ortho-McNeil Pharmaceutical, Inc.
- 当前专利权人地址: US NJ Raritan
- 代理商 Myra McCormack
- 主分类号: C12N15/00
- IPC分类号: C12N15/00 ; C12N15/12 ; C12N15/63 ; C07K14/00 ; C07H21/04
摘要:
The present invention provides nucleic acid and polypeptide sequences describing a novel isoform of the α2δ subunit of a voltage gated calcium channel, herein named as α2δ-4. The isolated nucleic acid or polypeptide molecule of the invention can be used in diagnosing and treating a disease or disorder associated with a defective α2δ-4 subunit, such as seizure-related syndromes, anxiety, multiple sclerosis, and the like.
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