Invention Grant
- Patent Title: Methods of treating joint inflammation with anti-TNF antibodies
- Patent Title (中): 用抗TNF抗体治疗关节炎症的方法
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Application No.: US10371443Application Date: 2003-02-21
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Publication No.: US07166284B2Publication Date: 2007-01-23
- Inventor: Junming Le , Jan Vilcek , Peter Daddona , John Ghrayeb , David Knight , Scott Siegel
- Applicant: Junming Le , Jan Vilcek , Peter Daddona , John Ghrayeb , David Knight , Scott Siegel
- Applicant Address: US NY New York US PA Malvern
- Assignee: New York University,Centocor, Inc.
- Current Assignee: New York University,Centocor, Inc.
- Current Assignee Address: US NY New York US PA Malvern
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28
Abstract:
Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
Public/Granted literature
- US20030198634A1 Methods of treating joint inflammation with chimeric anti-TNF antibodies Public/Granted day:2003-10-23
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