Invention Grant
US07166719B2 Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy 有权
与二氢卟酚和细菌毒素相关的氟光敏剂用于光动力疗法

Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy
Abstract:
Provided herein are compounds for detection, diagnosis and treatment of target tissues or target compositions, including hyperproliferative tissues such as tumors, using photodynamic methods. In particular, photosensitizer compounds that collect in hyperproliferative tissue are provided. In another embodiment, compounds that absorb light at a wavelength of from about 700 to about 850 nm are provided. In a further embodiment, compounds that are detectable by magnetic resonance imaging are provided.
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