发明授权
- 专利标题: Fluorescence detection of proteases or peptidases
- 专利标题(中): 荧光检测蛋白酶或肽酶
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申请号: US10240923申请日: 2001-04-06
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公开(公告)号: US07169574B2公开(公告)日: 2007-01-30
- 发明人: Bernard Pierre Roques , Nathalie Luciani , Marie-Claude Fournie-Zaluski , Hugues de Rocquigny
- 申请人: Bernard Pierre Roques , Nathalie Luciani , Marie-Claude Fournie-Zaluski , Hugues de Rocquigny
- 申请人地址: FR Paris FR Paris
- 专利权人: Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (C.N.R.S.)
- 当前专利权人: Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (C.N.R.S.)
- 当前专利权人地址: FR Paris FR Paris
- 代理机构: Stites & Harbison PLLC
- 代理商 B. Aaron Schulman
- 优先权: FR0004507 20000407
- 国际申请: PCT/FR01/01058 WO 20010406
- 国际公布: WO01/77369 WO 20011018
- 主分类号: C12Q1/37
- IPC分类号: C12Q1/37 ; C07K7/04 ; C07K7/08 ; C07K2/00 ; A61K38/00 ; A61K38/02 ; G01N33/53 ; A01N37/18
摘要:
The invention concerns the use of a PyA-(Z)x-pNF group in a substrate for detecting, identifying and/or analyzing by fluorometry peptidases or proteases capable of cleaving the or a bond between a PyA and pNF and/or compounds with inhibiting or activating activity with respect to enzymes capable of cleaving said bond.
公开/授权文献
- US20040214256A1 Fluorescence detection of proteases or peptidases 公开/授权日:2004-10-28
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