发明授权
- 专利标题： Cell isolation and screening device and method of using same
- 专利标题（中）： 细胞分离筛选装置及其使用方法
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申请号： US10206340申请日： 2002-07-29
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公开(公告)号： US07169577B2公开(公告)日： 2007-01-30
- 发明人: Evelyn Wang , Rocco Casagrande , Amar Kendale , Enoch Kim , Emanuele Ostuni , Olivier Schueller
- 申请人： Evelyn Wang , Rocco Casagrande , Amar Kendale , Enoch Kim , Emanuele Ostuni , Olivier Schueller
- 申请人地址： US MA Brighton
- 专利权人： Surface Logix, Inc.
- 当前专利权人： Surface Logix, Inc.
- 当前专利权人地址： US MA Brighton
- 代理机构： Kenyon & Kenyon LLP
- 主分类号： C12Q1/24
- IPC分类号： C12Q1/24
摘要：
The present invention provides methods and devices for screening a single cell or a small group of cells for a desired biological activity. In particular, the present invention provides for delivering cell(s) to a plurality of cell isolation regions of a cell isolation device, transferring cell(s) to a plurality of wells of a cell expansion device and then detecting the potential desired biological activity of the cell(s). Each of the receptacles comprise a recess sized to isolate a single cell or small group of cells and each of the wells encompass a cavity that provides sufficient volume for cell proliferation.
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