发明授权
US07172898B2 103P2D6: tissue specific protein highly expressed in various cancers
失效
103P2D6：在各种癌症中高度表达的组织特异性蛋白
- 专利标题： 103P2D6: tissue specific protein highly expressed in various cancers
- 专利标题（中）： 103P2D6：在各种癌症中高度表达的组织特异性蛋白
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申请号： US10283722申请日： 2002-10-29
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公开(公告)号： US07172898B2公开(公告)日： 2007-02-06
- 发明人: Arthur B. Raitano , Daniel E. H. Afar , Gazelle S. Rastegar , Steve Chappell Mitchell , Rene S. Hubert , Pia M. Challita-Eid , Mary Faris , Aya Jakobovits
- 申请人： Arthur B. Raitano , Daniel E. H. Afar , Gazelle S. Rastegar , Steve Chappell Mitchell , Rene S. Hubert , Pia M. Challita-Eid , Mary Faris , Aya Jakobovits
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12N15/63 ; C12N5/10 ; C12N1/15 ; C12N1/21
摘要：
A novel gene (designated 103P2D6) and its encoded protein are described. 103P2D6 is not expressed in normal adult tissue, but is highly expressed in prostate tissue xenografts, providing evidence that it is turned on in prostate cancer. 103P2D6 is also expressed in some fetal tissues, and in breast, bladder, lung, bone, colon, pancreatic, testicular, cervical and ovarian cancers. Consequently, 103P2D6 provides a diagnostic and/or therapeutic target for cancers, and the 103P2D6 gene or fragment thereof, or its encoded protein or a fragment thereof can be used to elicit an immune response.