发明授权
- 专利标题： Fused azepine derivatives and their use as antidiuretic agents
- 专利标题（中）： 稠合的吖庚因衍生物及其作为抗利尿剂的用途
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申请号： US10311301申请日： 2001-06-21
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公开(公告)号： US07176195B2公开(公告)日： 2007-02-13
- 发明人: Doreen Ashworth , Gary R. W. Pitt , Peter Hudson , Christopher Yea , Richard J. Franklin , Graeme Semple , David Paul Jenkins
- 申请人： Doreen Ashworth , Gary R. W. Pitt , Peter Hudson , Christopher Yea , Richard J. Franklin , Graeme Semple , David Paul Jenkins
- 申请人地址： NL Hoofddorp
- 专利权人： Ferring BV
- 当前专利权人： Ferring BV
- 当前专利权人地址： NL Hoofddorp
- 代理机构： Foley & Lardner LLP
- 优先权： GB0015601.8 20000626
- 国际申请： PCT/GB01/02737 WO 20010621
- 国际公布： WO02/00626 WO 20020103
- 主分类号： A61P7/12
- IPC分类号： A61P7/12 ; A61K31/55 ; C07D487/00 ; C07D498/00 ; C07D513/00
摘要：
Compounds according to general formulae (1 and 2), wherein G1 is an azepine derivative and G2 is a group according to general formulae (9–11) are new. Compounds according to the invention are vasopressin V2 receptor agonists. Pharmaceutical compositions of the compounds are useful as antidiuretic agents