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发明授权
US07176197B2 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid 有权
将伊伐布拉德及其加成盐与药学上可接受的酸合成的方法

Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
摘要：
Process for the synthesis of ivabradine of formula (I): addition salts with a pharmaceutically acceptable acid and hydrates thereof. α crystalline form of ivabradine hydrochloride.Medicinal products containing the a crystalline form of ivabradine hydrochloride, which are useful as bradycardics.
摘要（中）：

用于合成式（I）的伊伐布拉定的方法：与药学上可接受的酸和其水合物的加成盐。 盐酸伊伐布雷定的α晶型。 含有伊伐布雷定盐酸盐的结晶形式的药物，其可用作心动过缓。

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