发明授权
- 专利标题： Methods and compositions as protein kinase inhibitors
- 专利标题（中）： 方法和组成作为蛋白激酶抑制剂
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申请号： US10956412申请日： 2004-09-30
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公开(公告)号： US07189729B2公开(公告)日： 2007-03-13
- 发明人: Greg Chopiuk , Pascal Furet , Nathanael Schiander Gray , Patricia Imbach , Yi Liu , Joseph Schoepfer , Ruo Steensma
- 申请人： Greg Chopiuk , Pascal Furet , Nathanael Schiander Gray , Patricia Imbach , Yi Liu , Joseph Schoepfer , Ruo Steensma
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM Hamilton
- 代理机构： The Genomics Institute of the Novartis Research Foundation
- 代理商 Scott W. Reid
- 主分类号： C07D239/42
- IPC分类号： C07D239/42 ; C07D403/12 ; A61K31/506 ; A61P19/02 ; A61P35/00
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, EGF-R, c-erbB2 kinase (HER-2), CHK2, FGFR3, p70S6K, PKC, PDGF-R, p38, TGFβ, KDR, c-Kit, b-RAF, c-RAF, FLT1 and/or FLT4 kinases.
公开/授权文献
- US20050171105A1 Methods and compositions as protein kinase inhibitors 公开/授权日：2005-08-04
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