发明授权
- 专利标题： Phenylpropionic acid derivatives
- 专利标题（中）： 苯丙酸衍生物
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申请号： US10763237申请日： 2004-01-26
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公开(公告)号： US07193108B2公开(公告)日： 2007-03-20
- 发明人: Akira Chiba , Kazuyuki Sagi , Toshihiko Yoshimura , Tatsuya Okuzumi , Hiroyuki Izawa , Masahiro Murata
- 申请人： Akira Chiba , Kazuyuki Sagi , Toshihiko Yoshimura , Tatsuya Okuzumi , Hiroyuki Izawa , Masahiro Murata
- 申请人地址： JP Tokyo
- 专利权人： Ajinomoto Co., Inc.
- 当前专利权人： Ajinomoto Co., Inc.
- 当前专利权人地址： JP Tokyo
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权： JP2001-225749 20010726
- 主分类号： C07C315/00
- IPC分类号： C07C315/00 ; C07C317/00 ; C07C229/00 ; A61K31/00
摘要：
Specified phenylpropionic acid derivatives and analogues thereof have an antagonistic activity to α 4 integrin. They are used as therapeutic agents or preventive agents for various diseases concerning α 4 integrin, such as inflammatory diseases in which α 4 integrin-depending adhesion process participates in the pathology, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sjögren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection.
公开/授权文献
- US20040236147A1 Phenylpropionic acid derivatives 公开/授权日：2004-11-25
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