Invention Grant
- Patent Title: In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
- Patent Title (中): 用于评估纳米颗粒活性剂组合物的微粒剂型的体内效力的体外方法
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Application No.: US10323736Application Date: 2002-12-20
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Publication No.: US07198795B2Publication Date: 2007-04-03
- Inventor: Eugene R. Cooper , John A. Bullock , John R. Chippari , John L. Schaefer , Rakesh A. Patel , Rajeev Jain , Joost Strasters , Niels P. Ryde , Stephen B. Ruddy
- Applicant: Eugene R. Cooper , John A. Bullock , John R. Chippari , John L. Schaefer , Rakesh A. Patel , Rajeev Jain , Joost Strasters , Niels P. Ryde , Stephen B. Ruddy
- Applicant Address: IE Dublin
- Assignee: Elan Pharma International Ltd.
- Current Assignee: Elan Pharma International Ltd.
- Current Assignee Address: IE Dublin
- Agency: Foley & Lardner LLP
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/14 ; A61K9/08 ; A61K9/20 ; A61K9/48

Abstract:
Disclosed are in vitro methods for evaluating the in vivo redispersibility of dosage forms of poorly water-soluble active agents. The methods utilize media representative of in vivo human physiological conditions.
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