发明授权
US07198914B2 Guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37
失效
鸟苷三磷酸（GTP） - 结合蛋白偶联受体蛋白，BG37
- 专利标题： Guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37
- 专利标题（中）： 鸟苷三磷酸（GTP） - 结合蛋白偶联受体蛋白，BG37
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申请号： US10432101申请日： 2001-10-30
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公开(公告)号： US07198914B2公开(公告)日： 2007-04-03
- 发明人: Takaharu Maruyama , Takao Nakamura , Hiraku Itadani , Ken-Ichi Tanaka
- 申请人： Takaharu Maruyama , Takao Nakamura , Hiraku Itadani , Ken-Ichi Tanaka
- 申请人地址： JP Tokyo
- 专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Knobbe, Martens, Olson & Bear, LLP
- 优先权： JP2000-351741 20001117; JP2001-038619 20010215; JP2001-077000 20010316
- 国际申请： PCT/JP01/09512 WO 20011030
- 国际公布： WO02/40669 WO 20020523
- 主分类号： C12P21/06
- IPC分类号： C12P21/06 ; C07K5/00
摘要：
The present inventors conducted a similarity search of the amino acid sequence of known G protein-coupled receptor proteins in GenBank, and obtained a novel human GPCR gene “BG37”. cDNA containing the ORF of the gene was cloned and its nucleotide sequence was determined. Moreover, novel GPCR “BG37” genes from mouse and rat were isolated. Use of the novel GPCR of the present invention enables screening of ligands, compounds inhibiting the binding to a ligand, and candidate compounds of pharmaceuticals which can regulate signal transduction from the “BG37” receptor.
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