发明授权
- 专利标题： Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
- 专利标题（中）： 抑制巨噬细胞迁移抑制因子及其鉴定方法
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申请号： US11344938申请日： 2006-01-31
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公开(公告)号： US07202248B2公开(公告)日： 2007-04-10
- 发明人: Federico C. A. Gaeta , Andrew Baird , Jerry Anchin , Wenbin Ying , Robert Florkiewicz , Jagadish Sircar , Sunil Kumar K. C.
- 申请人： Federico C. A. Gaeta , Andrew Baird , Jerry Anchin , Wenbin Ying , Robert Florkiewicz , Jagadish Sircar , Sunil Kumar K. C.
- 申请人地址： US CA San Diego
- 专利权人： Avanir Pharmaceuticals
- 当前专利权人： Avanir Pharmaceuticals
- 当前专利权人地址： US CA San Diego
- 代理机构： Knobbe Martens Olson & Bear LLP
- 主分类号： A61K31/496
- IPC分类号： A61K31/496
摘要：
Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, X, Y and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.
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