Invention Grant
- Patent Title: Enhancement of transfection of DNA into the liver
- Patent Title (中): 增强DNA转染肝脏
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Application No.: US10483189Application Date: 2002-07-10
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Publication No.: US07211248B2Publication Date: 2007-05-01
- Inventor: Michael Davidson
- Applicant: Michael Davidson
- Applicant Address: US IL Glen Ellyn
- Assignee: SonoGene, L.L.C.
- Current Assignee: SonoGene, L.L.C.
- Current Assignee Address: US IL Glen Ellyn
- International Application: PCT/US02/21620 WO 20020710
- International Announcement: WO03/006608 WO 20030123
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A01N63/00
Abstract:
A method for transfection of DNA or RNA encoding apo A1 into the liver to regulate lipid metabolism comprises injection of a solution containing the DNA or RNA gene into the liver in combination with gas microbubbles or microspheres and using ultrasound to induce the transfection of the DNA or RNA in the liver.
Public/Granted literature
- US20040248832A1 Enhancement of transfection of dna into the liver Public/Granted day:2004-12-09
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