发明授权
US07211248B2 Enhancement of transfection of DNA into the liver 有权
增强DNA转染肝脏

  • 专利标题: Enhancement of transfection of DNA into the liver
  • 专利标题(中): 增强DNA转染肝脏
  • 申请号: US10483189
    申请日: 2002-07-10
  • 公开(公告)号: US07211248B2
    公开(公告)日: 2007-05-01
  • 发明人: Michael Davidson
  • 申请人: Michael Davidson
  • 申请人地址: US IL Glen Ellyn
  • 专利权人: SonoGene, L.L.C.
  • 当前专利权人: SonoGene, L.L.C.
  • 当前专利权人地址: US IL Glen Ellyn
  • 国际申请: PCT/US02/21620 WO 20020710
  • 国际公布: WO03/006608 WO 20030123
  • 主分类号: A61K48/00
  • IPC分类号: A61K48/00 A01N63/00
Enhancement of transfection of DNA into the liver
摘要:
A method for transfection of DNA or RNA encoding apo A1 into the liver to regulate lipid metabolism comprises injection of a solution containing the DNA or RNA gene into the liver in combination with gas microbubbles or microspheres and using ultrasound to induce the transfection of the DNA or RNA in the liver.
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