发明授权
- 专利标题： NK-1 receptor antagonists
- 专利标题（中）： NK-1受体拮抗剂
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申请号： US11376042申请日： 2006-03-15
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公开(公告)号： US07211579B2公开(公告)日： 2007-05-01
- 发明人: Christoph Funk , Torsten Hoffmann , Andreas Koblet
- 申请人： Christoph Funk , Torsten Hoffmann , Andreas Koblet
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- 优先权： EP05102359 20050323
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D213/75 ; C07D401/04
摘要：
The present invention relates to compounds of formula I wherein R is methyl; and R1 is 4-methyl-4-oxy-piperazin-1-yl; or R is CH2OH and R1 is 4-methyl-piperazin-1-yl or is 4-methyl-4-oxy-piperazin-1-yl; and to pharmaceutically acceptable acid addition salts thereof for the treatment of NK-1 receptor related diseases, for example depression, Parkinson's disease, Alzheimer's disease, anxiety, emesis, and pain.
公开/授权文献
- US20060217393A1 NK-1 receptor antagonists 公开/授权日：2006-09-28
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