发明授权
US07211594B2 Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
失效
吲唑化合物及其组合物作为JNK抑制剂和用于治疗与之相关的疾病
- 专利标题: Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
- 专利标题(中): 吲唑化合物及其组合物作为JNK抑制剂和用于治疗与之相关的疾病
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申请号: US10414839申请日: 2003-04-16
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公开(公告)号: US07211594B2公开(公告)日: 2007-05-01
- 发明人: Shripad S. Bhagwat , Yoshitaka Satoh , Steven T. Sakata , Chris A. Buhr , Ronald Albers , John Sapienza , Veronique Plantevin , Qi Chao , Kiran Sahasrabudhe , Rachel Ferri
- 申请人: Shripad S. Bhagwat , Yoshitaka Satoh , Steven T. Sakata , Chris A. Buhr , Ronald Albers , John Sapienza , Veronique Plantevin , Qi Chao , Kiran Sahasrabudhe , Rachel Ferri
- 申请人地址: US CA San Diego
- 专利权人: Signal Pharmaceuticals, LLC
- 当前专利权人: Signal Pharmaceuticals, LLC
- 当前专利权人地址: US CA San Diego
- 代理机构: Jones Day
- 主分类号: A61K31/416
- IPC分类号: A61K31/416 ; C07D231/56
摘要:
This invention is generally directed to Indazole Derivatives having the following structure: or pharmaceutically acceptable salt thereof, wherein R1, R2 and A are as defined herein. Such compounds have utility in the treatment of a wide range of diseases and disorders that are responsive to JNK inhibition, such as an inflammatory disease or disorder. Thus, methods of treating such diseases and disorders are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
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