发明授权
- 专利标题： Monocyclic substituted phenyl methanones
- 专利标题（中）： 单环取代苯甲酮
-
申请号： US11324990申请日： 2006-01-03
-
公开(公告)号： US07220744B2公开(公告)日： 2007-05-22
- 发明人: Synese Jolidon , Robert Narquizian , Roger David Norcross , Emmanuel Pinard
- 申请人： Synese Jolidon , Robert Narquizian , Roger David Norcross , Emmanuel Pinard
- 申请人地址： US NJ Nutley
- 专利权人： Hoffman-La Roche Inc.
- 当前专利权人： Hoffman-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- 优先权： EP051100077 20050107
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/496 ; C07D417/04 ; C07D417/14
摘要：
The present invention relates to compounds of formula I wherein R1, R2, X1, and X2 are as defined in the specification and to pharmaceutically acceptable acid addition salts thereof. Such compounds are inhibitors of the glycine transporter 1 (GlyT-1) and can be used in the treatment of schizophrenia, cognitive impairment, and Alzheimer's disease.
公开/授权文献
- US20060167009A1 Monocyclic substituted phenyl methanones 公开/授权日：2006-07-27
信息查询
IPC分类:
