A ligating apparatus includes an introducing tube which can be inserted in a living body cavity, a manipulating wire inserted in the introducing tube in such a manner that the manipulating wire can freely advance or retreat, a clip which is directly joined to a tip end of the manipulating wire, which has a holding portion formed in a tip end of an arm portion extending from the base end, and which has an extending/opening property, and engaging structure disposed in at least one of the base end of the clip and the tip end of the manipulating wire, wherein at least one of the engaging means is deformed and releases engaging of the clip and the manipulating wire, when the clip engages with the tip end of the introducing tube, and a force for detaching the base end of the clip from the tip end of the manipulating wire is applied.