发明授权
US07230001B1 Arylalkane, arylalkene and aryl azaalkane, medicaments containing said compounds and method for the production thereof
有权
芳基烷烃,芳基烯烃和芳基氮杂烷烃,含有所述化合物的药物及其制备方法
- 专利标题: Arylalkane, arylalkene and aryl azaalkane, medicaments containing said compounds and method for the production thereof
- 专利标题(中): 芳基烷烃,芳基烯烃和芳基氮杂烷烃,含有所述化合物的药物及其制备方法
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申请号: US10110347申请日: 2000-10-24
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公开(公告)号: US07230001B1公开(公告)日: 2007-06-12
- 发明人: Klaus Rudolf , Wolfgang Eberlein , Wolfhard Engel , Henri Doods , Gerhard Hallermayer , Eckhart Bauer
- 申请人: Klaus Rudolf , Wolfgang Eberlein , Wolfhard Engel , Henri Doods , Gerhard Hallermayer , Eckhart Bauer
- 申请人地址: DE Ingelheim
- 专利权人: Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人: Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址: DE Ingelheim
- 代理商 Michael P. Morris; Mary-Ellen M. Devlin; Alan R. Stempel
- 优先权: DE19952146 19991029
- 国际申请: PCT/EP00/10463 WO 20001024
- 国际公布: WO01/32649 WO 20010510
- 主分类号: C07D401/04
- IPC分类号: C07D401/04 ; A61K31/4523 ; C07D333/00
摘要:
The present invention relates to compounds of general formula R—Z1—Z2—Z3—R1, (I) wherein R, R1 and Z1 to Z3 are defined as in claim 1, the tautomers, the diastereomers, the enantiomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, particularly CGRP-antagonistic properties, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
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