Invention Grant
US07241581B2 Methods of identifying compounds that modulate IL-4 receptor-mediated IgE synthesis utilizing a c-MYC protein
有权
鉴定使用c-MYC蛋白调节IL-4受体介导的IgE合成的化合物的方法
- Patent Title: Methods of identifying compounds that modulate IL-4 receptor-mediated IgE synthesis utilizing a c-MYC protein
- Patent Title (中): 鉴定使用c-MYC蛋白调节IL-4受体介导的IgE合成的化合物的方法
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Application No.: US10222729Application Date: 2002-08-16
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Publication No.: US07241581B2Publication Date: 2007-07-10
- Inventor: Esteban Masuda , Todd M. Kinsella , Justin E. Warner , Taisei Kinoshita , Mark K. Bennett , David C. Anderson
- Applicant: Esteban Masuda , Todd M. Kinsella , Justin E. Warner , Taisei Kinoshita , Mark K. Bennett , David C. Anderson
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent James S. Keddie; Carol L. Francis; James J. Diehl
- Main IPC: G01N33/566
- IPC: G01N33/566 ; G01N33/53 ; G01N33/542 ; A61K38/20 ; A61K45/00
Abstract:
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a c-Myc protein as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
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