发明授权
US07241581B2 Methods of identifying compounds that modulate IL-4 receptor-mediated IgE synthesis utilizing a c-MYC protein
有权
鉴定使用c-MYC蛋白调节IL-4受体介导的IgE合成的化合物的方法
- 专利标题： Methods of identifying compounds that modulate IL-4 receptor-mediated IgE synthesis utilizing a c-MYC protein
- 专利标题（中）： 鉴定使用c-MYC蛋白调节IL-4受体介导的IgE合成的化合物的方法
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申请号： US10222729申请日： 2002-08-16
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公开(公告)号： US07241581B2公开(公告)日： 2007-07-10
- 发明人: Esteban Masuda , Todd M. Kinsella , Justin E. Warner , Taisei Kinoshita , Mark K. Bennett , David C. Anderson
- 申请人： Esteban Masuda , Todd M. Kinsella , Justin E. Warner , Taisei Kinoshita , Mark K. Bennett , David C. Anderson
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理商 James S. Keddie; Carol L. Francis; James J. Diehl
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; G01N33/53 ; G01N33/542 ; A61K38/20 ; A61K45/00
摘要：
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a c-Myc protein as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
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