Invention Grant
US07241598B2 Frame-shifting PCR for germline immunoglobulin genes retrieval and antibody engineering
有权
用于种系免疫球蛋白基因检索和抗体工程的帧转换PCR
- Patent Title: Frame-shifting PCR for germline immunoglobulin genes retrieval and antibody engineering
- Patent Title (中): 用于种系免疫球蛋白基因检索和抗体工程的帧转换PCR
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Application No.: US10880238Application Date: 2004-06-29
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Publication No.: US07241598B2Publication Date: 2007-07-10
- Inventor: Wing-Tai Cheung , Man Cheng
- Applicant: Wing-Tai Cheung , Man Cheng
- Applicant Address: CN Hong Kong SAR
- Assignee: The Chinese University of Hong Kong
- Current Assignee: The Chinese University of Hong Kong
- Current Assignee Address: CN Hong Kong SAR
- Agency: Occhiuti, Rohlicek & Tsao LLP
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12P21/00
Abstract:
A method for preparing an antigen-specific antibody by constructing a library of phage-displayed single chain variable fragment of an antibody with a novel frame-shifting PCR is disclosed. Also disclosed is a method for preparing a clone for producing an antigen-specific antibody.
Public/Granted literature
- US20050287538A1 Frame-shifting PCR for germline immunoglobulin genes retrieval and antibody engineering Public/Granted day:2005-12-29
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