Invention Grant
- Patent Title: Microorganisms and processes for enhanced production of pantothenate
- Patent Title (中): 用于增加泛酸盐生产的微生物和方法
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Application No.: US10466641Application Date: 2002-01-18
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Publication No.: US07244593B2Publication Date: 2007-07-17
- Inventor: R. Roger Yocum , Thomas A. Patterson , Janice G. Pero , Theron Hermann
- Applicant: R. Roger Yocum , Thomas A. Patterson , Janice G. Pero , Theron Hermann
- Applicant Address: DE
- Assignee: BASF Aktiengesellschaft
- Current Assignee: BASF Aktiengesellschaft
- Current Assignee Address: DE
- Agency: Lahive & Cockfield, LLP
- Agent Elizabeth A. Hanley, Esq.; Debra J. Milasincic, Esq.
- International Application: PCT/US02/00925 WO 20020118
- International Announcement: WO02/061108 WO 20020808
- Main IPC: C12P13/04
- IPC: C12P13/04
Abstract:
The present invention features improved methods for the enhanced production of pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities and having modified methylenetetrahydrofolate (MTF) biosynthetic enzyme activities. In particular, the invention features methods for enhancing production of desired products by increasing levels of a key intermediate, ketopantoate by enzymes that contribute to its synthesis. Recombinant microorganisms and conditions for culturing same are also are featured. Also featured are compositions produced by such microorganisms.
Public/Granted literature
- US20040091979A1 Microorganisms and processes for enhanced production of pantothenate Public/Granted day:2004-05-13
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