发明授权
- 专利标题： Polymerase chimeras
- 专利标题（中）： 聚合酶嵌合体
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申请号： US10456129申请日： 2003-06-06
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公开(公告)号： US07244602B2公开(公告)日： 2007-07-17
- 发明人: Bruno Frey , Britta Villbrandt , Dietmar Schomburg , Harald Sobek , Waltraud Ankenbauer
- 申请人： Bruno Frey , Britta Villbrandt , Dietmar Schomburg , Harald Sobek , Waltraud Ankenbauer
- 申请人地址： DE MAnnheim
- 专利权人： Roche Diagnostics GmbH
- 当前专利权人： Roche Diagnostics GmbH
- 当前专利权人地址： DE MAnnheim
- 代理机构： Townsend and Townsend and Crew
- 代理商 Charles M. Doyle; Khea C. Nersesian
- 优先权： DE19810879 19980313
- 主分类号： C12N9/12
- IPC分类号： C12N9/12 ; C12Q1/68
摘要：
The invention concerns polymerase chimeras which are composed of amino acid fragments representing domains and which combine properties of naturally occurring polymerases that are advantageous with regard to a particular application. It has surprisingly turned out that the domains from the various enzymes are active in the chimeras and exhibit cooperative behavior. In addition the present invention concerns a process for the production of the chimeras according to the invention and the use of these chimeras for the synthesis of nucleic acids e.g. during a polymerase chain reaction. Moreover the present invention concerns a kit which contains the polymerase chimeras according to the invention.
公开/授权文献
- US20040058362A1 Polymerase chimeras 公开/授权日：2004-03-25