Invention Grant
- Patent Title: Gamma-aminoamide modulators of chemokine receptor activity
- Patent Title (中): 趋化因子受体活性的γ-氨基酰胺调节剂
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Application No.: US10528329Application Date: 2003-10-24
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Publication No.: US07247725B2Publication Date: 2007-07-24
- Inventor: Gabor Butora , Alexander Pasternak , Lihu Yang , Changyou Zhou
- Applicant: Gabor Butora , Alexander Pasternak , Lihu Yang , Changyou Zhou
- Applicant Address: US NJ Rahway
- Assignee: Merck & Co., Inc.
- Current Assignee: Merck & Co., Inc.
- Current Assignee Address: US NJ Rahway
- Agent David Rubin; William Krovatin
- International Application: PCT/US03/34009 WO 20031024
- International Announcement: WO2004/041279 WO 20040521
- Main IPC: C07D221/20
- IPC: C07D221/20 ; A61K31/438
Abstract:
The present invention is directed to compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R11, R12, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
Public/Granted literature
- US20050261325A1 Gamma-aminoamide modulators of chemokine receptor activity Public/Granted day:2005-11-24
Information query
