Invention Grant
- Patent Title: Hydroxyethylamine derivatives for the treatment of Alzheimer's disease
- Patent Title (中): 羟乙胺衍生物用于治疗阿尔茨海默病
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Application No.: US10536303Application Date: 2003-12-03
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Publication No.: US07253198B2Publication Date: 2007-08-07
- Inventor: Emmanuel H Demont , Andrew Faller , David Timothy MacPherson , Peter Henry Milner , Alan Naylor , Sally Redshaw , Steven James Stanway , David R Vesey , Daryl S Walter
- Applicant: Emmanuel H Demont , Andrew Faller , David Timothy MacPherson , Peter Henry Milner , Alan Naylor , Sally Redshaw , Steven James Stanway , David R Vesey , Daryl S Walter
- Applicant Address: GB Greenford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Greenford, Middlesex
- Agent Bonnie L. Deppenbrock
- Priority: GB0228410.7 20021205
- International Application: PCT/EP03/13806 WO 20031203
- International Announcement: WO2004/050619 WO 20040617
- Main IPC: C07D275/03
- IPC: C07D275/03 ; C07D207/12 ; A61K31/425 ; A61K31/4015
Abstract:
The present invention relates to novel hydroxyethylamine compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
Public/Granted literature
- US20060025459A1 Hydroxyethylamine derivatives for the treatment of alzheimer's disease Public/Granted day:2006-02-02
Information query
