发明授权
- 专利标题： Anti human ovarian cancer-anti CD3 bispecific antibody
- 专利标题（中）： 抗人卵巢癌抗CD3双特异性抗体
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申请号： US10478345申请日： 2002-05-23
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公开(公告)号： US07262276B2公开(公告)日： 2007-08-28
- 发明人: Hualiang Huang , Xin Jiang , Min Fang , Xiaocong Yu , Jie Feng , Ping Zhou , Qing Lin
- 申请人： Hualiang Huang , Xin Jiang , Min Fang , Xiaocong Yu , Jie Feng , Ping Zhou , Qing Lin
- 申请人地址： CN Beijing
- 专利权人： Beijing ABT Genetic Engineering Technology Co. Ltd.
- 当前专利权人： Beijing ABT Genetic Engineering Technology Co. Ltd.
- 当前专利权人地址： CN Beijing
- 代理机构： Jones Day
- 优先权： CN01118247 20010524
- 国际申请： PCT/CN02/00347 WO 20020523
- 国际公布： WO03/004648 WO 20030116
- 主分类号： C07K16/30
- IPC分类号： C07K16/30
摘要：
The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.
公开/授权文献
- US20050255115A1 Anti human ovarian cancer-anti cd3 bispecific antibody 公开/授权日：2005-11-17
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