发明授权
- 专利标题： Anti-HLA-DR antibody
- 专利标题（中）： 抗HLA-DR抗体
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申请号： US10469304申请日： 2002-10-15
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公开(公告)号： US07262278B2公开(公告)日： 2007-08-28
- 发明人: Tomonori Tawara , Shiro Kataoka
- 申请人： Tomonori Tawara , Shiro Kataoka
- 申请人地址： JP Tokyo
- 专利权人： Kirin Beer Kabushiki Kaisha
- 当前专利权人： Kirin Beer Kabushiki Kaisha
- 当前专利权人地址： JP Tokyo
- 代理机构： Foley & Lardner LLP
- 优先权： JP2001-317054 20011015
- 国际申请： PCT/JP02/10665 WO 20021015
- 国际公布： WO03/033538 WO 20030424
- 主分类号： C12P21/08
- IPC分类号： C12P21/08 ; C07K16/28
摘要：
This invention provides an anti-HLA-DR monoclonal antibody. This invention relates to an antibody binding to HLA-DR or a functional fragment thereof having (a) life-extending effects in nonhuman animals bearing HLA-DR-expressing cancer cells and (b) activity of suppressing immune responses lower than that of L243, or an antibody binding to HLA-DR or a functional fragment thereof exhibiting immunosuppressive activity equivalent to or higher than that of the mouse anti-HLA-DR monoclonal antibody L243 (ATCC HB-55).
公开/授权文献
- US20040091974A1 Anti-hla-dr antibody 公开/授权日：2004-05-13
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