发明授权
US07265116B2 Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof
失效
芳基和杂芳基取代的四氢异喹啉及其用途
- 专利标题： Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof
- 专利标题（中）： 芳基和杂芳基取代的四氢异喹啉及其用途
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申请号： US10917801申请日： 2004-08-13
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公开(公告)号： US07265116B2公开(公告)日： 2007-09-04
- 发明人: James P. Beck , Matt A. Curry , Mark A. Smith
- 申请人： James P. Beck , Matt A. Curry , Mark A. Smith
- 申请人地址： US VT Manchester Center
- 专利权人： ARM Technology, Inc.
- 当前专利权人： ARM Technology, Inc.
- 当前专利权人地址： US VT Manchester Center
- 代理机构： Nixon Peabody LLP
- 主分类号： A61K31/50
- IPC分类号： A61K31/50
摘要：
Provided herein are compounds of the formula (I): wherein R1-R8 are as described herein, R4 being phthalazinyl, pyrazinyl, pyridazinyl, or quinoxalinyl. Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine, or dopamine.
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