发明授权
- 专利标题： Inhalation particles incorporating a combination of two or more active ingredients
- 专利标题（中）： 掺入两种或多种活性成分的组合的吸入颗粒
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申请号： US10398373申请日： 2001-10-05
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公开(公告)号： US07267813B2公开(公告)日： 2007-09-11
- 发明人: Wiwik Watanabe , Esko Kauppinen , Petri Ahonen , David Brown , Esa Muttonen
- 申请人： Wiwik Watanabe , Esko Kauppinen , Petri Ahonen , David Brown , Esa Muttonen
- 申请人地址： FI Espoo
- 专利权人： Orion Corporation
- 当前专利权人： Orion Corporation
- 当前专利权人地址： FI Espoo
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 优先权： FI20002215 20001006
- 国际申请： PCT/FI01/00863 WO 20011005
- 国际公布： WO02/28377 WO 20020411
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K9/12 ; A61K31/56
摘要：
Crystalline spherical inhalation particles incorporating a combination of two or more different active ingredients and a process for the preparation thereof. The particles have a narrow particle size distribution, rough surfaces and improved stability. The inhalation particles of the invention are particularly useful in the administration of a combination medicament, e.g. a combination of an anti-inflammatory agent and a bronchodilator, by inhalation in the treatment of asthma and other respiratory disorders.
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