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6 条记录 (耗时 0.017 秒)

    Combination particles for the treatment of asthma
    1.
    发明授权
    Combination particles for the treatment of asthma 有权
    用于治疗哮喘的组合颗粒

    公开(公告)号：US07172752B2

    公开(公告)日：2007-02-06

    申请号：US10398381

    申请日：2001-10-05

    申请人： Wiwik Watanabe ,  Esko Kauppinen ,  Petri Ahonen ,  David Brown ,  Esa Muttonen

    发明人： Wiwik Watanabe ,  Esko Kauppinen ,  Petri Ahonen ,  David Brown ,  Esa Muttonen

    IPC分类号： A61K9/14 ,  A61K9/12 ,  A61K31/56

    CPC分类号： A61K9/0075 ,  A61K31/57 ,  Y10S514/826 ,  A61K31/165 ,  A61K2300/00

    摘要： Inhalation particles incorporating, in an individual particle, a combination of a βhd 2-agonist and a glucocorticosteroid in a predetermined and constant ratio, a process for the preparation thereof and pharmaceutical compositions comprising the inhalation particles. The particles have a narrow particle size distribution and are preferably in the form of spherical crystalline particles with a rough surface. The particles are particularly useful in the treatment of asthma and other respiratory disorders.

    摘要翻译： 吸入颗粒在单个颗粒中以预定和恒定的比例结合β-胡萝卜素2-激动剂和糖皮质激素的组合，其制备方法和包含吸入颗粒的药物组合物。 颗粒具有窄的粒度分布，并且优选具有粗糙表面的球形结晶颗粒的形式。 这些颗粒特别适用于治疗哮喘和其他呼吸系统疾病。

    Single, multi-walled, functionalized and doped carbon nanotubes and composites thereof
    5.
    发明申请
    Single, multi-walled, functionalized and doped carbon nanotubes and composites thereof 有权
    单层，多壁，功能化和掺杂的碳纳米管及其复合材料

    公开(公告)号：US20070148962A1

    公开(公告)日：2007-06-28

    申请号：US10591954

    申请日：2005-03-09

    申请人： Esko Kauppinen ,  David Brown ,  Albert Nasibulin ,  Hua Jiang ,  Anna Moisala

    发明人： Esko Kauppinen ,  David Brown ,  Albert Nasibulin ,  Hua Jiang ,  Anna Moisala

    IPC分类号： H01L21/4763 ,  H01L21/302

    CPC分类号： C01B31/024 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/162 ,  C01B32/164 ,  C01B32/174 ,  C01B2202/02 ,  C01B2202/06 ,  C01B2202/34 ,  C01B2202/36 ,  C01P2004/04 ,  C01P2004/13 ,  C01P2004/133 ,  H01M4/583 ,  H01M4/96 ,  Y10S977/843

    摘要： The present invention relates to single walled and multi-walled carbon nanotubes (CNTs), functionalized CNTs and carbon nanotube composites with controlled properties, to a method for aerosol synthesis of single walled and multi-walled carbon nanotubes, functionalized CNTs and carbon nanotube composites with controlled properties from pre-made catalyst particles and a carbon source in the presence of reagents and additives, to functional, matrix and composite materials composed thereof and structures and devices fabricated from the same in continuous or batch CNT reactors. The present invention allows all or part of the processes of synthesis of CNTs, their purification, doping, functionalization, coating, mixing and deposition to be combined in one continuous procedure and in which the catalyst synthesis, the CNT synthesis, and their functionalization, doping, coating, mixing and deposition can be separately controlled.

    摘要翻译： 本发明涉及具有受控性质的单壁和多壁碳纳米管（CNT），官能化CNT和碳纳米管复合材料，用于单壁和多壁碳纳米管的气溶胶合成方法，官能化CNT和碳纳米管复合材料，其具有 在试剂和添加剂存在下，预制催化剂颗粒和碳源的控制性质，由其组成的功能性，基质和复合材料以及在连续或间歇CNT反应器中由其制备的结构和器件。 本发明允许在一个连续的过程中组合CNT的全部或部分合成方法，其纯化，掺杂，官能化，涂覆，混合和沉积，其中催化剂合成，CNT合成及其官能化掺杂 ，涂层，混合和沉积可以单独控制。

    Dry powder inhaler
    6.
    发明授权
    Dry powder inhaler 有权
    干粉吸入器

    公开(公告)号：US06983748B2

    公开(公告)日：2006-01-10

    申请号：US10399913

    申请日：2001-10-26

    申请人： David Brown ,  Esko Kauppinen ,  Juha Kurkela ,  Wiwik Watanabe ,  Jorma Jokiniemi ,  Esa Muttonen

    发明人： David Brown ,  Esko Kauppinen ,  Juha Kurkela ,  Wiwik Watanabe ,  Jorma Jokiniemi ,  Esa Muttonen

    IPC分类号： A61M15/00

    CPC分类号： A61M15/0065 ,  A61M2202/064 ,  A61M2206/14

    摘要： A device for delivering a powdered medicament by inhalation comprises an air inlet passage having low pressure-drop and low turbulence for stabilizing air flow before aerosolization, a dosing cup in the region of reduced air velocity to delay aerosolization, a high pressure drop throat to generate a high velocity flow, a rapidly expanding diverging passage to create a free jet of air with high turbulence and an outlet passage having large cross-sectional area to control the rate of dissipation of the free jet. The device is simple yet capable of consistently providing uniform and effective powder aerosolization and deagglomeration over a variety of patient inhalation profiles.

    摘要翻译： 用于通过吸入输送粉末药物的装置包括空气入口通道，其具有低压降和低湍流，用于在气雾化之前稳定空气流，在减小空气速度的区域中的计量杯以延迟气雾化，产生高压降喉 高速流动，快速扩张的扩张通道以产生具有高湍流的空气的自由射流和具有大横截面面积的出口通道以控制自由射流的耗散速率。 该装置简单，但能够持续提供均匀有效的粉雾雾化和各种患者吸入曲线上的解聚。