发明授权
- 专利标题: Neurotoxins with enhanced target specificity
- 专利标题(中): 具有增强靶特异性的神经毒素
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申请号: US09726949申请日: 2000-11-29
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公开(公告)号: US07273722B2公开(公告)日: 2007-09-25
- 发明人: Wei-Jen Lin , Kei Roger Aoki , Lance E. Steward
- 申请人: Wei-Jen Lin , Kei Roger Aoki , Lance E. Steward
- 申请人地址: US CA Irvine
- 专利权人: Allergan, Inc.
- 当前专利权人: Allergan, Inc.
- 当前专利权人地址: US CA Irvine
- 代理商 Dean G. Stathakis; Joel B. German; Martin A. Voet
- 主分类号: C12P21/06
- IPC分类号: C12P21/06
摘要:
Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle or selectively inactivated by proteases in blood.
公开/授权文献
- US20020137886A1 Neurotoxins with enhanced target specificity 公开/授权日:2002-09-26
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