发明授权
- 专利标题： Tri-peptide hepatitis C serine protease inhibitors
- 专利标题（中）： 三肽丙型肝炎丝氨酸蛋白酶抑制剂
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申请号： US10849107申请日： 2004-05-19
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公开(公告)号： US07273851B2公开(公告)日： 2007-09-25
- 发明人: Zhenwei Miao , Ying Sun , Suanne Nakajima , Datong Tang , Zhe Wang , Yat S. Or
- 申请人： Zhenwei Miao , Ying Sun , Suanne Nakajima , Datong Tang , Zhe Wang , Yat S. Or
- 申请人地址： US MA Watertown
- 专利权人： Enanta Pharmaceuticals, Inc.
- 当前专利权人： Enanta Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Watertown
- 代理机构： Edwards Angell Palmer & Dodge LLC
- 代理商 Jeffrey Hsi
- 主分类号： A61K38/00
- IPC分类号： A61K38/00
摘要：
The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
公开/授权文献
- US20050261200A1 Tri-peptide hepatitis C serine protease inhibitors 公开/授权日：2005-11-24
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