发明授权
US07279280B2 Apparatus and method for detecting genetic mutations and single nucleotide polymorphisms
失效
用于检测遗传突变和单核苷酸多态性的装置和方法
- 专利标题: Apparatus and method for detecting genetic mutations and single nucleotide polymorphisms
- 专利标题(中): 用于检测遗传突变和单核苷酸多态性的装置和方法
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申请号: US10949761申请日: 2004-09-25
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公开(公告)号: US07279280B2公开(公告)日: 2007-10-09
- 发明人: Michael Pappas , Zhuying Wang
- 申请人: Michael Pappas , Zhuying Wang
- 申请人地址: US NJ Lawrenceville
- 专利权人: MGP Biotech, Inc.
- 当前专利权人: MGP Biotech, Inc.
- 当前专利权人地址: US NJ Lawrenceville
- 代理机构: Altimatia, LLC
- 代理商 David M. Gange
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H21/02 ; C07H21/04
摘要:
A method and means of identifying nucleic acid oligomers is disclosed. A sample is split into parts and the parts are flowed through chromatography columns containing nucleic acid oligomer probes bound to a binding medium. Analyte oligomers are transiently hybridized to complementary probe oligomers during chromatography. Detection and analysis of oligomer peaks is used to identify the oligomers contained in the sample.
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