Invention Grant
US07282199B2 Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
有权
腺相关病毒（AAV）血清型8序列，含有其的载体及其用途
- Patent Title: Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
- Patent Title (中): 腺相关病毒（AAV）血清型8序列，含有其的载体及其用途
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Application No.: US10423704Application Date: 2003-04-25
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Publication No.: US07282199B2Publication Date: 2007-10-16
- Inventor: Guangping Gao , James M. Wilson , Mauricio R. Alvira
- Applicant: Guangping Gao , James M. Wilson , Mauricio R. Alvira
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Howson & Howson LLP
- Main IPC: C12N15/864
- IPC: C12N15/864 ; C12N15/35 ; C12N15/63 ; C12N15/64 ; C12N7/01 ; C12P21/00 ; C07K14/015 ; C12Q1/70 ; C12Q1/68
Abstract:
Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. rAAV8-mediated delivery of therapeutic and immunogenic genes, including Factor VIII, is also provided.
Public/Granted literature
- US20030228282A1 Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor Public/Granted day:2003-12-11
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