发明授权
- 专利标题: Method and device for determining distribution of glycation of erythrocytic membranes
- 专利标题(中): 用于确定红细胞膜糖基化分布的方法和装置
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申请号: US10903077申请日: 2004-07-30
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公开(公告)号: US07288412B2公开(公告)日: 2007-10-30
- 发明人: Osamu Nozaki , Hiroko Kawamoto , Motonori Munesue
- 申请人: Osamu Nozaki , Hiroko Kawamoto , Motonori Munesue
- 代理机构: Akin Gump Strauss Hauer & Feld LLP
- 优先权: JP2003-204441 20030731
- 主分类号: G01N33/48
- IPC分类号: G01N33/48
摘要:
A method for determining the distribution of glycation of erythrocytic membranes includes steps of bonding magnetic beads having a boric acid group with sugars on the surfaces of erythrocytic membranes, and moving the erythrocytes bonded with the boric acid-magnetic beads under an influence of an electromagnetic force. A device for determining the distribution of glycation of erythrocytic membranes includes a container as a cell for electromagnetic-phoresis, a cathode ray and an anode ray which are connected to a direct current power supply, and a magnetic sheet which is placed outside the bottom of the container. The container has an upper surface containing a cathode hole, an anode hole, a filling hole midway between the cathode hole and the anode hole for a specimen, and an excretory hole for releasing air bubbles. After physiological saline is poured into the container, the cathode ray and the anode ray are respectively inserted into the holes to be soaked in the saline. Subsequently, a specimen of erythrocytes, which are bonded with the boric acid-magnetic beads, is infused into the container through the filling hole.
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