发明授权
- 专利标题： Bradykinin-B1 antagonists, process for their preparation and their use as medicaments
- 专利标题（中）： 缓激肽B1拮抗剂，其制备方法及其用作药物
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申请号： US11256573申请日： 2005-10-21
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公开(公告)号： US07291642B2公开(公告)日： 2007-11-06
- 发明人: Iris Kauffmann-Hefner , Norbert Hauel , Henri Doods , Angelo Ceci , Stefan Peters
- 申请人： Iris Kauffmann-Hefner , Norbert Hauel , Henri Doods , Angelo Ceci , Stefan Peters
- 申请人地址： DE Ingelheim
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： DE Ingelheim
- 代理商 Michael P. Morris; Mary-Ellen M. Devlin; Alan R. Stempel
- 优先权： DE102004054053 20041105; DE102005013967 20050326
- 主分类号： A61K31/4164
- IPC分类号： A61K31/4164 ; A61K31/4709 ; A61K31/4439 ; A61K31/501 ; A61K31/5513 ; A61K31/513 ; A61K31/454 ; C07D233/04 ; C07D233/06
摘要：
The present invention provides bradykinin-B1 antagonists of the formula in which A, Ar, G, Q, R1 and R4 are as defined in claim 1, their enantiomers, their diastereomers, their mixtures and their salts, in particular their physiologically acceptable salts with organic or inorganic acids or bases having useful properties, their preparation, medicaments comprising the pharmacologically effective compounds, their preparation and their use.
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