发明授权
US07294646B2 Maxi-k channel blockers, methods of use and process for making the same
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Maxi-k通道阻滞剂,使用方法和制备方法
- 专利标题: Maxi-k channel blockers, methods of use and process for making the same
- 专利标题(中): Maxi-k通道阻滞剂,使用方法和制备方法
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申请号: US10511731申请日: 2003-06-13
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公开(公告)号: US07294646B2公开(公告)日: 2007-11-13
- 发明人: Maria L. Garcia , Michael A. Goetz , Gregory J. Kaczorowski , Owen B. McManus , Richard L. Monaghan , William R. Strohl , Jan S. Tkacz
- 申请人: Maria L. Garcia , Michael A. Goetz , Gregory J. Kaczorowski , Owen B. McManus , Richard L. Monaghan , William R. Strohl , Jan S. Tkacz
- 申请人地址: US NJ Rahway
- 专利权人: Merck & Co. Inc.
- 当前专利权人: Merck & Co. Inc.
- 当前专利权人地址: US NJ Rahway
- 代理商 Sylvia A. Ayler; William Krovatin
- 国际申请: PCT/US03/18842 WO 20030613
- 国际公布: WO03/105724 WO 20031224
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; C07D487/00
摘要:
This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of a mammalian species, particularly humans.
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