Invention Grant
US07309577B2 Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
有权
使用T1R1 / T1R3（鲜味）味觉受体的结合测定法鉴定引发或调节鲜味的化合物
- Patent Title: Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
- Patent Title (中): 使用T1R1 / T1R3（鲜味）味觉受体的结合测定法鉴定引发或调节鲜味的化合物
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Application No.: US10725418Application Date: 2003-12-03
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Publication No.: US07309577B2Publication Date: 2007-12-18
- Inventor: Mark Zoller , Xiaodong Li , Lena Staszewski , Shawn O'Connell , Sergey Zozulya , Jon Elliot Adler , Hong Xu , Fernando Echeverri
- Applicant: Mark Zoller , Xiaodong Li , Lena Staszewski , Shawn O'Connell , Sergey Zozulya , Jon Elliot Adler , Hong Xu , Fernando Echeverri
- Applicant Address: US CA San Diego
- Assignee: Senomyx, Inc.
- Current Assignee: Senomyx, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Hunton & Williams LLP
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/567
Abstract:
Binding assays for identifying compounds that induce or modulate the T1R1/T1R3 (umami) receptor-associated taste are provided. These binding assays detect the specific binding of a compound to a T1R1/T1R3 (umami) taste receptor or detect the modulation (inhibition or enhancement) of the binding of another compound, e.g., L-glutamate, L-aspartate or lactisole to a T1R1/T1R3 umami taste receptor. Compounds that are identified in these binding assays have potential application as T1R1/T1R3 umami taste modulators and therefore can be used as flavor additives in compositions for human or animal consumption.
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