发明授权
US07309721B2 Aminoalkylphosphonates and related compounds as Edg receptor agonists
失效
氨基烷基膦酸盐和相关化合物作为Edg受体激动剂
- 专利标题： Aminoalkylphosphonates and related compounds as Edg receptor agonists
- 专利标题（中）： 氨基烷基膦酸盐和相关化合物作为Edg受体激动剂
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申请号： US10505257申请日： 2003-02-27
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公开(公告)号： US07309721B2公开(公告)日： 2007-12-18
- 发明人: Richard J. Budhu , George A. Doherty , Jeffrey J. Hale , Christopher L. Lynch , Sander G. Mills , William E. Neway, III
- 申请人： Richard J. Budhu , George A. Doherty , Jeffrey J. Hale , Christopher L. Lynch , Sander G. Mills , William E. Neway, III
- 申请人地址： US NJ Rahway
- 专利权人： Merck + Co., Inc.
- 当前专利权人： Merck + Co., Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 William Krovatin; Raynard Yuro
- 国际申请： PCT/US03/05947 WO 20030227
- 国际公布： WO03/073986 WO 20030912
- 主分类号： A61K31/185
- IPC分类号： A61K31/185 ; A61K31/4196 ; A61K31/4192 ; A61K31/417 ; A61K31/41 ; C07D257/04 ; C07D233/84 ; C07D249/04 ; C07D249/12 ; C07F9/02
摘要：
The present invention encompasses compounds or Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
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