发明授权
US07314764B2 Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
有权
用于生物应用的有机发光半导体纳米晶体探针和用于制造和使用这种探针的方法
- 专利标题： Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
- 专利标题（中）： 用于生物应用的有机发光半导体纳米晶体探针和用于制造和使用这种探针的方法
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申请号： US11370656申请日： 2006-03-07
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公开(公告)号： US07314764B2公开(公告)日： 2008-01-01
- 发明人: Shimon Weiss , Marcel Bruchez, Jr. , Paul Alivisatos
- 申请人： Shimon Weiss , Marcel Bruchez, Jr. , Paul Alivisatos
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Bozicevic, Field & Francis LLP
- 代理商 Karl Bozicevic
- 主分类号： G01N33/552
- IPC分类号： G01N33/552
摘要：
A semiconductor nanocrystal compound is described capable of linking to an affinity molecule. The compound comprises (1) a semiconductor nanocrystal capable of emitting electromagnetic radiation and/or absorbing energy, and/or scattering or diffracting electromagnetic radiation—when excited by an electromagnetic radiation source or a particle beam; and (2) an affinity molecule linked to the semiconductor nanocrystal. The semiconductor nanocrystal is linked to an affinity molecule to form a semiconductor nanocrystal probe capable of bonding with a detectable substance. Exposure of the semiconductor nanocrystal to excitation energy will excite the semiconductor nanocrystal causing the emission of electromagnetic radiation. Further described are processes for respectively: making the luminescent semiconductor nanocrystal compound; making the semiconductor nanocrystal probe; and using the probe to determine the presence of a detectable substance in a material.
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