发明授权
US07320992B2 Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use
有权
取代的2,3-二氢-1,5-异吲哚-1-酮衍生物及其使用方法
- 专利标题: Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use
- 专利标题(中): 取代的2,3-二氢-1,5-异吲哚-1-酮衍生物及其使用方法
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申请号: US10926238申请日: 2004-08-24
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公开(公告)号: US07320992B2公开(公告)日: 2008-01-22
- 发明人: Christopher Tegley , Jeffrey A. Adams , Benny C. Askew, Jr. , Michael Croghan , Daniel Elbaum , Julie Germain , Gregory J. Habgood , Scott Harried , Aiwen Li , Nobuko Nishimura , Rana Nomak , Andrew Tasker , Kevin Yang
- 申请人: Christopher Tegley , Jeffrey A. Adams , Benny C. Askew, Jr. , Michael Croghan , Daniel Elbaum , Julie Germain , Gregory J. Habgood , Scott Harried , Aiwen Li , Nobuko Nishimura , Rana Nomak , Andrew Tasker , Kevin Yang
- 申请人地址: US CA Thousand Oaks
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: US CA Thousand Oaks
- 代理商 Joseph W. Bulock; Ronald S. Hermenau
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; C07D401/12
摘要:
Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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