发明授权
US07323456B2 Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient
失效
羧酸衍生物化合物和包含该化合物作为活性成分的试剂
- 专利标题: Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient
- 专利标题(中): 羧酸衍生物化合物和包含该化合物作为活性成分的试剂
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申请号: US10495158申请日: 2002-11-11
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公开(公告)号: US07323456B2公开(公告)日: 2008-01-29
- 发明人: Hisao Tajima , Yoshisuke Nakayama
- 申请人: Hisao Tajima , Yoshisuke Nakayama
- 申请人地址: JP Osaka
- 专利权人: Ono Pharmaceutical Co., Ltd.
- 当前专利权人: Ono Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Osaka
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2001-346583 20011112
- 国际申请: PCT/JP02/11729 WO 20021111
- 国际公布: WO03/042194 WO 20030522
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; C07D413/10 ; C07D417/10
摘要:
A compound of formula (I) (wherein all symbols are as defined in the specification) and a salt thereof, and peroxisome proliferator activated receptor regulator comprising thereof as active ingredient. Because a compound of formula (I) have an activity of regulating peroxisome proliferator activated receptor regulator, the compound of formula (I) is useful as a hypoglycemic agent, a hypolipidemic agent, a preventive and/or treatment agent for diseases associating metabolic disorders (diabetes, obesity, syndrome X, hypercholesterolemia, hyperlipoproteinemia, etc.), hyperlipemia, atherosclerosis, hypertension, circulatory diseases, overeating, ischemic heart diseases, etc., an HDL cholesterol-elevating agent, an LDL cholesterol and/or VLDL cholesterol-lowering agent and a drug for relief from risk factors of diabetes or syndrome X.
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