发明授权
- 专利标题: Melanin concentrating hormone receptor ligands
- 专利标题(中): 黑色素浓缩激素受体配体
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申请号: US10820344申请日: 2004-04-08
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公开(公告)号: US07323478B2公开(公告)日: 2008-01-29
- 发明人: Rajagopal Bakthavatchalam , Andrew Thurkauf , Alan Hutchison
- 申请人: Rajagopal Bakthavatchalam , Andrew Thurkauf , Alan Hutchison
- 申请人地址: US CT Branford
- 专利权人: Neurogen Corporation
- 当前专利权人: Neurogen Corporation
- 当前专利权人地址: US CT Branford
- 代理商 Ann T. Kadlecek; Seth A. Fidel
- 主分类号: A61K31/445
- IPC分类号: A61K31/445
摘要:
Disclosed are compounds of the formula: and the pharmaceutically acceptable salts thereof wherein Q, X, Y, Z, and R1 R9, and R12-R19 are defined herein. These compounds are selective modulators of MCH 1 receptors that are, therefore, useful in the treatment of a variety of metabolic, feeding, and sexual disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also disclosed.
公开/授权文献
- US20040229883A1 Melanin concentrating hormone receptor ligands 公开/授权日:2004-11-18
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