发明授权
- 专利标题: Process for preparation of optically active allenes
- 专利标题(中): 光学活性聚烯烃的制备方法
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申请号: US10506573申请日: 2002-09-06
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公开(公告)号: US07326559B2公开(公告)日: 2008-02-05
- 发明人: Keisuke Suzuki , Takashi Matsumoto
- 申请人: Keisuke Suzuki , Takashi Matsumoto
- 申请人地址: JP Saitama
- 专利权人: Japan Science and Technology Agency
- 当前专利权人: Japan Science and Technology Agency
- 当前专利权人地址: JP Saitama
- 代理机构: Foley & Lardner LLP
- 优先权: JP2002-061014 20020306
- 国际申请: PCT/JP02/09085 WO 20020906
- 国际公布: WO03/074717 WO 20030912
- 主分类号: C12P41/00
- IPC分类号: C12P41/00
摘要:
The present invention provides a process for producing an optically active allene represented by formula (1): wherein R2 and R3 are different and each represents a hydrogen atom, an optionally substituted C1-20 alkyl group or an optionally substituted C6-20 aryl group, and R4 represents an acyl group, which comprises reacting an allene derivative represented by formula (2): wherein R1 represents a hydrogen atom or an optionally substituted acyl group and R2 and R3 have the same meaning as defined above, with an acylating agent having an acyl group represented by R4 when both R1s are each a hydrogen atom or with water when both R1s are each an acyl group represented by R4, in the presence of an enzyme catalyst. According to this production process, an optically active allene can be produced efficiently and enantioselectively from an allene derivative having a symmetrical structure.
公开/授权文献
- US20050106692A1 Process for preparation of optically active allenes 公开/授权日:2005-05-19